The DYMO LabelManager 420P ($110 street) falls in the rarest sub-category of label printers. To begin with, it doesn't print paper labels for envelopes and the like. Instead, it prints plastic (and other) labels suitable for computer cables, outdoor labeling, or for things like your stapler so it...
Prints labels both from a computer and as a completely self-contained handheld labeling system.
Keyboard arrangement is alphabetical rather than QWERTY